Bilirubin Total and Indirect Bilirubin
Rate: Rs. 200
Sample
This test is done on the serum of patient.
Important facts
1.Raised Bilirubins is the indicator of liver dysfunction.
Basically this is the end product of Hemoglobin metabolism.
1.Bilirubin is one componant of bile which is transported from liver and stored in gall bladder.
Normal adult values
Total bilirubin :0.3–1.0 mg/dL or 5.1–17.0 mmol/L
Direct bilirubin : 0.1–0.3 mg/dL or 1.0–5.1 mmol/L
Indirect bilirubin : (total bilirubin level minus direct bilirubin level)= 0.2–0.7 mg/dL or 3.4–11.9 mmol/L
Total bilirubin in
1.Umblical cord blood : less than 2 mg/ dl.
2.Infants
1.0—1 days : less tha 6 mg/ dl
2.0—2 days : less than 8 mg/ dl
3.3—5 days : less than 12 mg/dl
4.after 5 days : less tha .2 to 1.0mg/ dl
High values
:High levels of bilirubin in the blood may be caused by:
1.Some infections, such as an infected gallbladder, or cholecystitis.
2.Some inherited diseases, such as Gilbert’s syndrome.Although jaundice may occur in some people with Gilbert’s syndrome, the condition is not harmful.
3.Diseases that cause liver damage, such as hepatitis, cirrhosis, or mononucleosis.
4.Diseases that cause blockage of the bile ducts, such as gallstones or cancer of the pancreas.
5.Rapid destruction of red blood cells in the blood, such as from sickle cell disease or an allergic reaction to blood received during a transfusion (called a transfusion reaction).
6.Medicines that may increase bilirubin levels. This includes many antibiotics, some types of birth control pills, indomethacin (Indocin), phenytoin (Dilantin), diazepam (Valium), and flurazepam (Dalmane).
Low values
:Low levels of bilirubin in the blood may be caused by:
Medicines that may decrease bilirubin levels. This includes vitamin C (ascorbic acid), phenobarbital, and theophylline.
Bilirubin levels that may require treatment in a full-term, healthy baby:
24 hours or younger:
More than 10 mg/dL or more than 170 mmol/L
25 to 48 hours:
More than 15 mg/dL or more than 255 mmol/L
49 to 72 hours:
More than 18 mg/dL or more than 305 mmol/L
Older than 72 hours:
More than 20 mg/dL or more than 340 mmol/L
Important
Bilirubinuria is present in obstructive and parenchymal jaundice but absent in hemolytic jaundice.
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